IMMUNOHISTOCHEMISTRY, E-CADHERIN

What this test checks

Detects E-Cadherin protein in tissue, which helps distinguish between two types of breast cancer (lobular vs. ductal) and assess how likely cancer cells are to spread.

Why do people get this test?

E-Cadherin loss is a hallmark of lobular breast cancer. Identifying the correct breast cancer subtype ensures the most appropriate surgical and treatment decisions are made.

When you should consider this test

• When classifying breast cancer subtype (lobular vs. ductal)
• When assessing invasion or spread potential of a tumour
• As part of a breast cancer diagnostic panel

How to prepare

No preparation needed — performed on biopsy or surgical tissue.