IMMUNOHISTOCHEMISTRY, CD 45 (LCA)

What this test checks

Detects CD45 (Leukocyte Common Antigen), a marker present on virtually all white blood cells. Used to confirm that a tumour is a lymphoma (cancer of lymph cells) rather than a carcinoma.

Why do people get this test?

The first question when evaluating any lymph node or soft tissue mass is: is this a lymphoma or a different cancer type? CD45 provides a quick, reliable answer that guides the entire diagnostic pathway.

When you should consider this test

• When evaluating a lymph node mass or other tumour for possible lymphoma
• When an undifferentiated tumour needs to be classified
• As part of initial lymphoma work-up

How to prepare

No preparation needed — performed on biopsy or surgical tissue.