IMMUNOHISTOCHEMISTRY, CD 15

What this test checks

Detects CD15, expressed on Reed-Sternberg cells in Hodgkin lymphoma — the characteristic giant cells that define this cancer. Key marker for confirming Hodgkin lymphoma diagnosis.

Why do people get this test?

Hodgkin lymphoma is one of the most curable cancers when correctly identified. CD15, combined with CD30, confirms classical Hodgkin lymphoma and distinguishes it from other lymphomas that require completely different treatment.

When you should consider this test

• When Hodgkin lymphoma is suspected
• When classifying lymphomas involving lymph nodes, mediastinum, or spleen
• As part of Hodgkin lymphoma diagnostic panel (CD15/CD30)

How to prepare

No preparation needed — performed on biopsy or surgical tissue.