IMMUNOHISTOCHEMISTRY, CD 117

What this test checks

Detects the CD117 (c-KIT) protein marker on tumour cells. This marker is essential for identifying gastrointestinal stromal tumours (GIST) and some other cancers, and determines eligibility for targeted drugs like imatinib.

Why do people get this test?

CD117-positive GIST tumours respond dramatically to targeted therapy (imatinib/gleevec). This test confirms diagnosis and treatment eligibility — potentially life-saving information.

When you should consider this test

• When a tumour in the stomach, intestine, or abdominal cavity is suspected to be GIST
• Before starting targeted therapy for GIST
• When classifying an abdominal soft tissue tumour

How to prepare

No preparation needed — performed on biopsy or surgical tissue.